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Scientists at Spain’s Cima Universidad de Navarra have discovered that inhaling menthol can regulate the immune system and improve cognitive function in animals suffering from neurodegenerative diseases, including Alzheimer’s.

Graphical Abstract – Improved Cognitive Functionl…

Alzheimer’s disease is a common form of dementia that affects memory, thinking, and behavior. It typically develops slowly over several years and can result in severe impairment of daily living. The symptoms of Alzheimer’s disease include forgetfulness, confusion, difficulty with problem-solving and decision-making, mood swings, changes in personality and behavior, and trouble with language and communication. As the disease progresses, individuals with Alzheimer’s disease may require assistance with basic daily tasks and may eventually become unable to care for themselves independently. Currently, there is no cure for Alzheimer’s disease, but medications and lifestyle changes can help to manage its symptoms and slow its progression. In addition to physical decline, Alzheimer’s disease also affects personality and behavior, often leading to changes in mood, social withdrawal, agitation, and impaired judgment. It can be challenging for families and caregivers to manage these changes, but understanding the disease and seeking support can help.

Despite the challenges posed by Alzheimer’s disease, many individuals are able to live fulfilling lives with appropriate support and care. By understanding the disease and its symptoms, seeking appropriate medical care and support, and making necessary lifestyle changes, individuals with Alzheimer’s disease and their families can manage the disease and maintain quality of life for as long as possible.

Now, thanks to the research at Cima Universidad de Navarra, there may be another possible treatment that can reduce the effects of the disease and offer some protection.

Menthol is an organic compound created using various types of mints and has several applications, including use in cough and cold products and topical pain relief. Researchers found that even brief exposure to the substance could prevent cognitive deterioration typical of the condition and may open the door to creating new odor-based therapies to reverse the effects of Alzheimer’s – the most common form of dementia worldwide.

The findings suggest there may be an important connection between the immune system, the central nervous system, and smell when it comes to the prevention and treatment of Alzheimer’s.

Read the study > Improvement of cognitive function in wild-type and Alzheimer´s disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells

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